Efficacy of 5 diets on settlement and development of the sea louse Lepeophtheirus salmonis on Atlantic salmon
The purpose/aim of the study:
The aim of the trial is to quantify effects of 5 trial diets against settlement and early development of the salmon louse, Lepeophtheirus salmonis.
Expected adverse effects on the animals:
It is not expected substantially adverse effects on the trial fish throughout the trial onto the termination. The impact on trial fish is expected to be low based on the use of sedation and termination of the trial at a stadium prior to the point that Lepeophtheirus salmonis will give skin lessions or in other ways harm the fish.
The expected scientific and social utility/value of the study:
Lepeophtheirus salmonis is a serious problem both regarding animal welfare, environmental impact and the aquaculture industry. Maintaining focus on detection and efficacy evaluation of preventive agents are therefore deemed to possess significance positive effects on animal welfare, safeguarding of environment and providing social benefits. The study is considered thereof having both scientific and social utility and value.
The number and identification of animals:
900 seaworthy smolt from Atlantic salmon will be used in the trial.
How the demands for replacement, reduction and refinement will be complied:
There are no real alternatives to in vivo testing to evaluate efficacy in feed trials with Lepeophtheirus salmonis on Atlantic salmon. The trial cannot be replaced with other models without compromising the validity of the test result, and hence increase the need for repeated experiments. The number of fish is taken down to a minimum from being able to provide statistically acceptable results and usefulness of the results. Acclimatization, sedation and monitoring procedures are optimalized to reduce the risk negative impact from trial on the fish.
The aim of the trial is to quantify effects of 5 trial diets against settlement and early development of the salmon louse, Lepeophtheirus salmonis.
Expected adverse effects on the animals:
It is not expected substantially adverse effects on the trial fish throughout the trial onto the termination. The impact on trial fish is expected to be low based on the use of sedation and termination of the trial at a stadium prior to the point that Lepeophtheirus salmonis will give skin lessions or in other ways harm the fish.
The expected scientific and social utility/value of the study:
Lepeophtheirus salmonis is a serious problem both regarding animal welfare, environmental impact and the aquaculture industry. Maintaining focus on detection and efficacy evaluation of preventive agents are therefore deemed to possess significance positive effects on animal welfare, safeguarding of environment and providing social benefits. The study is considered thereof having both scientific and social utility and value.
The number and identification of animals:
900 seaworthy smolt from Atlantic salmon will be used in the trial.
How the demands for replacement, reduction and refinement will be complied:
There are no real alternatives to in vivo testing to evaluate efficacy in feed trials with Lepeophtheirus salmonis on Atlantic salmon. The trial cannot be replaced with other models without compromising the validity of the test result, and hence increase the need for repeated experiments. The number of fish is taken down to a minimum from being able to provide statistically acceptable results and usefulness of the results. Acclimatization, sedation and monitoring procedures are optimalized to reduce the risk negative impact from trial on the fish.