The impact of different protein sources in a western diet

The main aim is to detect the impact of different protein sources in a western diet on development of obesity and type 2 diabetes. The direct impact of several different protein sources of relevance for a western intake will be evaluated in mice according to development of obesity and type 2 diabetes. This study is performed in order to detect the direct causative effect of the different protein sources evaluated and to identify possible changes in important mechanisms related to obesity and type 2 diabetes. 130 female C57BL/6J mice will be included in this animal trial. All animal handling will be performed by experienced staff, and care is taken to minimize stress imposed on the animals during procedures. No invasive procedures are planned during the experiment. The experimental set-up is performed in order to minimize the stress of the animals and reduce animals to lowest possible number. A whole organism is necesseary in order to detect whole body metabolism involved in the development of diet induced obesity and diabetes.